Start from unlocked systems
World Tree Holy Water is not an early checklist item. First confirm which late-game systems your save can actually use. If expeditions are ready, plan around expedition uptime. If fishing is safer, prepare bait, travel, and inventory. If a pond-supported route is available, treat it as a base workflow instead of a single pickup.
Compare expedition and fishing friction
The fastest route is the one with the least repeated friction in your world. Expeditions may be cleaner if the roster and timing are ready. Fishing may be better if travel and bait are already solved. A base-supported loop may win once workers, storage, and route timing are stable.
Spend only after the target is clear
Because Holy Water sits near late-game progression, do not spend the first batch casually. Check the exact craft, unlock, or upgrade first, then decide whether one more test loop is needed before scaling the route.